Cow Transmembrane and ubiquitin-like domain-containing protein 1 (TMUB1) ELISA Kit

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AE14089BO
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Product Name Cow Transmembrane and ubiquitin-like domain-containing protein 1 (TMUB1) ELISA Kit
Description Tmub1 encodes for a protein, HOPS/DULP, containing transmembrane domains and a ubiquitin-like domain (UBL) Ubiquitin can be employed to modify proteins by either single or multiple ubiquitin conjugation to mark them for proteasomal destruction, endocytosis and binding to other proteins. Tmub1/HOPS was reported to facilitate the recycling of AMPA receptors into synaptic membrane in cultured primary neurons. Tmub1/HOPS was also found overexpressed during liver regeneration and is an essential constituent of centrosome assembly during cell cycles in culture. Like many UBL domain proteins, the physiological and molecular function of Tmub1 is far from being clear. The resulting mice Tmub1were put through an extensive battery of assays to discover physiological and behavioral phenotypes. This assay has high sensitivity and excellent specificity for detection of Bovine TMUB1. No significant cross-reactivity or interference between Bovine TMUB1 and analogues was observed.
Synonyms C7orf21, MGC5442, SB144,
Method Sandwich ELISA
Detection Range Request Information
Sensitivity Request Information
Reactivity Bovine
Sample Types Serum, Plasma, Other biological fluids.
Background Tmub1 encodes for a protein, HOPS/DULP, containing transmembrane domains and a ubiquitin-like domain (UBL) Ubiquitin can be employed to modify proteins by either single or multiple ubiquitin conjugation to mark them for proteasomal destruction, endocytosis and binding to other proteins. Tmub1/HOPS was reported to facilitate the recycling of AMPA receptors into synaptic membrane in cultured primary neurons. Tmub1/HOPS was also found overexpressed during liver regeneration and is an essential constituent of centrosome assembly during cell cycles in culture. Like many UBL domain proteins, the physiological and molecular function of Tmub1 is far from being clear. The resulting mice Tmub1were put through an extensive battery of assays to discover physiological and behavioral phenotypes.
Supplier Abebio

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