| Product Name | Cow Xanthine dehydrogenase/oxidase (XDH) ELISA Kit |
|---|---|
| Description | Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. The three substrates of this enzyme are xanthine, NAD+, and H2O, whereas its three products are urate, NADH, and H+.This enzyme belongs to the family of oxidoreductases, to be specific, those acting on CH or CH2 group with NAD+ or NADP+ as acceptor.Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. This assay has high sensitivity and excellent specificity for detection of Bovine XDH. No significant cross-reactivity or interference between Bovine XDH and analogues was observed. |
| Synonyms | XO, XOR, xanthene dehydrogenase|xanthine oxidase|xanthine oxidoreductase |
| Method | Sandwich ELISA |
| Detection Range | 0.781-50 ng/mL |
| Sensitivity | 0.27 ng/mL |
| Reactivity | Bovine |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background |
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. The three substrates of this enzyme are xanthine, NAD+, and H2O, whereas its three products are urate, NADH, and H+.This enzyme belongs to the family of oxidoreductases, to be specific, those acting on CH or CH2 group with NAD+ or NADP+ as acceptor.Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. |
| Supplier | Abebio |
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