| Product Name | COX11 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to COX11 |
| Synonyms | COX11 antibody; COX11 homolog antibody; COX11 homolog; cytochrome c oxidase assembly protein (yeast) antibody; COX11_HUMAN antibody; COX11P antibody; Cytochrome c oxidase assembly protein COX11 antibody; Cytochrome c oxidase assembly protein COX11; mitochondrial antibody; Cytochrome c oxidase subunit 11 antibody; mitochondrial antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human COX11 |
| Isotype | IgG |
| Target | COX11 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q9Y6N1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. |
| Supplier | Cusabio |
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