| Product Name | CPEB1 Antibody, FITC conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against CPEB1 conjugated to FITC |
| Synonyms | CEBP antibody; CPE binding protein 1 antibody; CPE BP1 antibody; CPE-binding protein 1 antibody; CPE-BP1 antibody; CPEB 1 antibody; CPEB antibody; CPEB-1 antibody; CPEB1 antibody; CPEB1 protein antibody; CPEB1_HUMAN antibody; Cytoplasmic polyadenylation binding protein 1 antibody; Cytoplasmic polyadenylation element binding protein antibody; Cytoplasmic polyadenylation element binding protein 1 antibody; Cytoplasmic polyadenylation element-binding protein 1 antibody; FLJ13203 antibody; h CEBP antibody; h-CEBP antibody; hCPEB 1 antibody; hCPEB-1 antibody; MGC34136 antibody; MGC60106 antibody; mKIAA0940 antibody; MKIAA0940 protein antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | FITC |
| Immunogen | Recombinant human Cytoplasmic polyadenylation element-binding protein 1 protein (1-486AA) |
| Isotype | IgG |
| Target | CPEB1 |
| Reactivity | Human |
| Applications | ELISA, Dot Blot |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q9BZB8 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress. |
| Supplier | Cusabio |
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