| Product Name | CRTAM Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CRTAM |
| Synonyms | CD355 antibody; Class I MHC restricted T cell associated molecule antibody; Class-I MHC-restricted T-cell-associated molecule antibody; CRTAM antibody; CRTAM_HUMAN antibody; Cytotoxic and regulatory T cell molecule antibody; Cytotoxic and regulatory T-cell molecule antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human CRTAM |
| Isotype | IgG |
| Target | CRTAM |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | O95727 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. |
| Supplier | Cusabio |
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