| Product Name | CSRP2, 1-193aa, Human |
|---|---|
| Description | CSRP2 (Cysteine and glycine-rich protein 2) is a member of the CSRP family, contains 2 LIM zinc-binding domains, which may be involved in regulatory processes important for development and cellular differentiation. This protein plays a role in the development of the embryonic vascular system. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Recombinant human CSRP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | cysteine and glycine-rich protein 2, CRP2, LMO5, SmLIM |
| Host | E. coli |
| Molecular Weight | 10.5 kDa(97aa), confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMPVWGG GNKCGACGRT VYHAEEVQCD GRSFHRCCFL CMVCRKNLDS TTVAIHDEEI YCKSCYGKKY GPKGYGYGQG AGTLNMDRGE RLGIKPESVQ PHRPTTNPNT SKFAQKYGGA EKCSRCGDSV YAAEKIIGAG KPWHKNCFRC AKCGKSLEST TLTEKEGEIY CKGCYAKNFG PKGFGYGQGA GALVHAQ |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl, |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Weiskirchen R, et al. (2000). Biochem. Biophys. Res. Commun. 274 (3): 655-63. Jain MK, et al. (1996). J. Biol. Chem. 271 (17): 10194-9. |
| Background | CSRP2 (Cysteine and glycine-rich protein 2) is a member of the CSRP family, contains 2 LIM zinc-binding domains, which may be involved in regulatory processes important for development and cellular differentiation. This protein plays a role in the development of the embryonic vascular system. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Recombinant human CSRP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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