| Product Name | CTDSP1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CTDSP1 |
| Synonyms | Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody; CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1 antibody; CTD small phosphatase 1 antibody; CTDS1_HUMAN antibody; CTDSP1 antibody; NIF3 antibody; NLI IF antibody; NLI interacting factor 3 antibody; NLI-IF antibody; NLI-interacting factor 3 antibody; NLIIF antibody; Nuclear LIM interactor interacting factor 3 antibody; Nuclear LIM interactor-interacting factor 3 antibody; SCP1 antibody; Small C-terminal domain phosphatase 1 antibody; Small CTD phosphatase 1 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from N-terminal of human CTDSP1. |
| Isotype | IgG |
| Target | CTDSP1 |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | Q9GZU7 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Marquet S., Mamm. Genome 11:755-762(2000). Yeo M., J. Biol. Chem. 278:26078-26085(2003). Hillier L.W., Nature 434:724-731(2005) |
| Supplier | Cusabio |
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