| Product Name | CTLA4 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CTLA4 |
| Synonyms | ALPS5 antibody; CD 152 antibody; CD antibody; CD152 antibody; CD152 antigen antibody; CD152 isoform antibody; Celiac disease 3 antibody; CELIAC3 antibody; CTLA 4 antibody; CTLA-4 antibody; CTLA4 antibody; CTLA4_HUMAN antibody; Cytotoxic T cell associated 4 antibody; Cytotoxic T lymphocyte antigen 4 antibody; Cytotoxic T lymphocyte associated 4 antibody; Cytotoxic T lymphocyte associated 4, soluble isoform, included antibody; Cytotoxic T lymphocyte associated antigen 4 antibody; Cytotoxic T lymphocyte associated antigen 4 short spliced form antibody; Cytotoxic T lymphocyte associated protein 4 antibody; Cytotoxic T lymphocyte associated serine esterase 4 antibody; Cytotoxic T lymphocyte protein 4 antibody; Cytotoxic T-lymphocyte protein 4 antibody; Cytotoxic T-lymphocyte-associated antigen 4 antibody; GRD4 antibody; GSE antibody; ICOS antibody; IDDM12 antibody; insulin-dependent diabetes mellitus 12 antibody; Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4 antibody; OTTHUMP00000216623 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to residues near the C terminal of human Cytotoxic T-lymphocyte protein 4 |
| Isotype | IgG |
| Target | CTLA4 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
| Uniprot | P16410 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
| Supplier | Cusabio |
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