CXCL8 (54-72) scrambled control

Category: Bioreagents
Catalog
IM-020
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Product Name CXCL8 (54-72) scrambled control
Description CXCL8 (54-72) scrambled control, also referred to as Peptide 3, is the scrambled peptide containing the wild-type amino acids of CXCL8 (54-72) in random order for use as a control.  CXCL8 (54-72), is the C-terminal CXCL8 peptide fragment corresponding to the core CXCL8 - glycosaminoglycan (GAG) binding region which binds to GAG during neutrophil recruitment to reduce neutrophil adhesion and migration during the inflammatory response.
Synonyms Peptide 3
Molecular Weight 2401.75 Da
Target Protein-protein interactions,Chemokine receptors
Amino Acid Sequence Ac-KVREKNEKWFVEQRVALNS-NH2
Form Freeze dried solid
Purity >95% by HPLC
Storage Store dry, frozen and in the dark
Notes Modifications: N terminal acetylation, C terminal amidation
References Martínez€Burgo et al (2019), A C€terminal CXCL 8 peptide based on chemokine-glycosaminoglycan interactions reduces neutrophil adhesion and migration during inflammation. Immunol. 157 173 PMID: 31013364
Related areas
All peptides >All chemokine receptor modulators >All adhesion molecule research categories >All immunology research categories >
Supplier Isca Biochemicals Limited

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