| Product Name | CYP3A4 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CYP3A4 |
| Synonyms | 1,8-cineole 2-exo-monooxygenase antibody; Albendazole monooxygenase antibody; Albendazole sulfoxidase antibody; CP33 antibody; CP34 antibody; CP3A4_HUMAN antibody; CYP3 antibody; CYP3A antibody; CYP3A3 antibody; CYP3A4 antibody; CYPIIIA3 antibody; CYPIIIA4 antibody; Cytochrome P450 3A3 antibody; Cytochrome P450 3A4 antibody; Cytochrome P450 family 3 subfamily A polypeptide 4 antibody; Cytochrome P450 HLp antibody; Cytochrome P450 NF-25 antibody; Cytochrome P450 subfamily IIIA polypeptide 4 antibody; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 antibody; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody; Cytochrome P450-PCN1 antibody; Glucocorticoid inducible P450 antibody; HLP antibody; MGC126680 antibody; NF 25 antibody; NF25 antibody; Nifedipine oxidase antibody; P450 III steroid inducible antibody; P450 PCN1 antibody; P450, family III antibody; P450C3 antibody; P450PCN1 antibody; Quinine 3 monooxygenase antibody; Quinine 3-monooxygenase antibody; Taurochenodeoxycholate 6 alpha hydroxylase antibody; Taurochenodeoxycholate 6-alpha-hydroxylase antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from internal of human Cytochrome P450 3A4. |
| Isotype | IgG |
| Target | CYP3A4 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | P08684 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide. Vuoristo M.M., J. Biol. Chem. 270:22873-22881(1995). Mungall A.J., Nature 425:805-811(2003). Lui V.C., Genomics 32:401-412(1996). |
| Supplier | Cusabio |
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