| Product Name | CYR61 Antibody, HRP conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against CYR61 conjugated to HRP. |
| Synonyms | 3CH61 antibody; CCN 1 antibody; CCN family member 1 antibody; CCN1 antibody; CYR 61 antibody; Cyr61 antibody; CYR61 protein antibody; CYR61_HUMAN antibody; Cysteine rich angiogenic inducer 61 antibody; Cysteine rich heparin binding protein 61 antibody; Cysteine-rich angiogenic inducer 61 antibody; GIG 1 antibody; GIG1 antibody; IBP-10 antibody; IGF-binding protein 10 antibody; Igfbp 10 antibody; IGFBP-10 antibody; Igfbp10 antibody; Insulin like growth factor binding protein 10 antibody; Insulin-like growth factor-binding protein 10 antibody; Protein CYR61 antibody; Protein GIG1 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | HRP |
| Immunogen | Recombinant Human Protein CYR61 protein (25-381AA) |
| Isotype | IgG |
| Target | CYR61 |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | O00622 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3. |
| Supplier | Cusabio |
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