| Product Name | DENR, 1-198aa, Human |
|---|---|
| Description | DENR may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. This protein plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. Recombinant human DENR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Density-regulated protein, DRP, DRP1, SMAP-3 |
| Host | E. coli |
| Molecular Weight | 24.7 kDa (216aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MAADISESSG ADCKGDPRNS AKLDADYPLR VLYCGVCSLP TEYCEYMPDV AKCRQWLEKN FPNEFAKLTV ENSPKQEAGI SEGQGTAGEE EEKKKQKRGG RGQIKQKKKT VPQKVTIAKI PRAKKKYVTR VCGLATFEID LKEAQRFFAQ KFSCGASVTG EDEIIIQGDF TDDIIDVIQE KWPEVDDDSI EDLGEVKK |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 5% glycerol, 0.4M Urea |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| Purity | > 85 % by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Deyo JE., et al. (1998) DNA Cell Biol. 17(5):437-47. Oh JJ., et al. (1999) Nucleic Acids Res. 27(20):4008-17. |
| Background | DENR may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. This protein plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1. Recombinant human DENR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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