| Product Name | DHX36 Antibody, Biotin conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against DHX36 conjugated to Biotin. |
| Synonyms | DDX36 antibody; DEAH box protein 36 antibody; Dhx36 antibody; DHX36_HUMAN antibody; EC 3.6.1.- antibody; KIAA1488 antibody; MLE like protein 1 antibody; MLE-like protein 1 antibody; MLEL1 antibody; Probable ATP dependent RNA helicase DHX36 antibody; Probable ATP-dependent RNA helicase DHX36 antibody; RHAU antibody; RNA helicase associated with AU rich element ARE antibody; RNA helicase associated with AU-rich element ARE antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant Human ATP-dependent RNA helicase DHX36 protein (68-181AA) |
| Isotype | IgG |
| Target | DHX36 |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q9H2U1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation; the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification. |
| Supplier | Cusabio |
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