| Product Name | Dio3 Antibody, HRP conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against Type III iodothyronine deiodinase conjugated to HRP |
| Synonyms | Dio3 antibody; Itdi3 antibody; Txdi3 antibody; Thyroxine 5-deiodinase antibody; EC 1.21.99.3 antibody; 5DIII antibody; DIOIII antibody; Type 3 DI antibody; Type III iodothyronine deiodinase antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | HRP |
| Immunogen | Recombinant rat Type III iodothyronine deiodinase protein (37-278AA) |
| Isotype | IgG |
| Target | Dio3 |
| Reactivity | Rat |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | P49897 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development. |
| Supplier | Cusabio |
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