DNAJB1 Antibody

Category: Antibodies
Catalog
CSB-PA795084
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Product Name DNAJB1 Antibody
Description Rabbit polyclonal antibody to DNAJB1
Synonyms DnaJ (Hsp40) homolog subfmaily B member 1 antibody; DNAJ 1 antibody; DNAJ B1 antibody; DnaJ heat shock protein family (Hsp40) member B1 antibody; DnaJ homolog subfamily B member 1 antibody; DnaJ protein homolog 1 antibody; DNAJ1 antibody; DNAJB 1 antibody; Dnajb1 antibody; DNAJB1 protein antibody; DNJB1_HUMAN antibody; HDJ 1 antibody; HDJ-1 antibody; HDJ1 antibody; Heat shock 40 kDa protein 1 antibody; Heat shock 40kD protein 1 antibody; Heat shock protein 40 antibody; Hsp 40 antibody; HSP40 antibody; HSPF 1 antibody; HSPF1 antibody; Human DnaJ protein 1 antibody; Radial spoke 16 homolog B antibody; RSPH16B antibody; Sis1 antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Fusion protein of human DNAJB1
Isotype IgG
Target DNAJB1
Reactivity Human, Mouse
Applications ELISA, IHC
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot P25685
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
References
  1. Shinde, V. et al. RNA sequencing of corneas from two keratoconus patient groups identifies potential biomarkers and decreased NRF2-antioxidant responses. Sci Rep 10, 9907 (2020)
Background DnaJ homolog subfamily B member 1 is a protein that in humans is encoded by the DNAJB1 gene. Heat shock protein 40 (HSP 40) family proteins bind to HSP 70 through their J-domain and regulate the function of HSP 70 by stimulating HSP 70 ATPase activity. HSP 40, also known as DnaJ, functions together with DnaK (HSP 70) and GrpE as a molecular chaperone, involving them in assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. HSP 40 stimulates the association between HSC 70 and HIP and translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock.
Supplier Cusabio

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