DOCK1 Antibody, HRP conjugated

Category: Antibodies
Catalog
CSB-PA619864LB01HU
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Product Name DOCK1 Antibody, HRP conjugated
Description Rabbit polyclonal antibody against DOCK1 conjugated to HRP
Synonyms 180 kDa protein downstream of CRK antibody; Ced5 antibody; Dedicator of Cytokinesis 1 antibody; Dedicator of cytokinesis protein 1 antibody; DOCK 1 antibody; DOCK 180 antibody; DOCK1 antibody; DOCK1_HUMAN antibody; DOCK180 antibody
Host Rabbit
Clonality Polyclonal
Conjugate HRP
Immunogen Recombinant Human Dedicator of cytokinesis protein 1 protein (1676-1865AA)
Isotype IgG
Target DOCK1
Reactivity Human
Applications ELISA
Form Liquid
Diluent Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Uniprot Q14185
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).
Supplier Cusabio

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