| Product Name | DOCK3 Antibody, FITC conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against DOCK3 conjugated to FITC. |
| Synonyms | DOCK3 antibody; KIAA0299 antibody; MOCADedicator of cytokinesis protein 3 antibody; Modifier of cell adhesion antibody; Presenilin-binding protein antibody; PBP antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | FITC |
| Immunogen | Recombinant human Dedicator of cytokinesis protein 3 protein (1630-1934AA) |
| Isotype | IgG |
| Target | DOCK3 |
| Reactivity | Human |
| Applications | ELISA, Dot Blot |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q8IZD9 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity). |
| Supplier | Cusabio |
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