| Product Name | Canine Gastrin (GAST) ELISA Kit |
|---|---|
| Description | Gastrin is a major physiological regulator of gastric acid secretion. It also has an important trophic or growth-promoting influence on the gastric mucosa. Gastrin is synthesized in G cells, which are located in gastric pits, primarily in the antrum region of the stomach and binds receptors found predominantly on parietal and enterochromaffin-like cells.In humans, gastrin is a hormone that stimulates secretion of gastric acid by the parietal cells of the stomach. It is released by G cells in the stomach and duodenum.Gastrin is a linear peptide hormone produced by G cells of the duodenum and in the pyloric antrum of the stomach. In the Zollinger-Ellison syndrome, gastrin is produced at excessive levels, often by a gastrinoma of the antrum or the pancreas. Canine Gastrin (GAST) ELISA Kit employs a two-site sandwich ELISA to quantitate Gastrin in samples. An antibody specific for Gastrin has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any Gastrin present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugate Canine Gastrin detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of Gastrin bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | GAST, GAS, |
| Method | Sandwich ELISA |
| Detection Range | 3.75 ng/L-60 ng/L |
| Sensitivity | 0.1 ng/L |
| Reactivity | Canine |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 100685087 |
| Storage | 2-8°C |
| Background |
Gastrin is a major physiological regulator of gastric acid secretion. It also has an important trophic or growth-promoting influence on the gastric mucosa. Gastrin is synthesized in G cells, which are located in gastric pits, primarily in the antrum region of the stomach and binds receptors found predominantly on parietal and enterochromaffin-like cells.In humans, gastrin is a hormone that stimulates secretion of gastric acid by the parietal cells of the stomach. It is released by G cells in the stomach and duodenum.Gastrin is a linear peptide hormone produced by G cells of the duodenum and in the pyloric antrum of the stomach. In the Zollinger-Ellison syndrome, gastrin is produced at excessive levels, often by a gastrinoma of the antrum or the pancreas. |
| Supplier | Abbkine |
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