| Product Name | Canine Taste receptor type 1 member 2 (TAS1R2) ELISA Kit |
|---|---|
| Description | Canine Taste receptor type 1 member 2 (TAS1R2) ELISA Kit has high sensitivity and excellent specificity for detection of Canine TAS1R2. No significant cross-reactivity or interference between Canine TAS1R2 and analogues was observed. Taste receptor type 1 member 2 (TAS1R2) is a G protein-coupled receptor with seven trans-membrane domains and is a component of the heterodimeric amino acid taste receptor T1R2+3. TAS1R2 is formed as a dimer of the TAS1R2 and TAS1R3 proteins. Moreover, the TAS1R2 protein is not functional without formation of the 2+3 heterodimer. Another interesting quality of the TAS1R2 and TAS1R1 genes is their spontaneous activity in the absence of the extracellular domains and binding ligands. This may mean that the extracellular domain regulates function of the receptor by preventing spontaneous action as well as binding to activating ligands such as sucrose. This Canine Taste receptor type 1 member 2 (TAS1R2) ELISA Kit employs a two-site sandwich ELISA to quantitate TAS1R2 in samples. An antibody specific for TAS1R2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyTAS1R2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TAS1R2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TAS1R2 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | TAS1R2, GPR71, T1R2, TR2, G protein-coupled receptor 71 |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Canine |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 478213 |
| Storage | 2-8°C |
| Background | Taste receptor type 1 member 2 (TAS1R2) is a G protein-coupled receptor with seven trans-membrane domains and is a component of the heterodimeric amino acid taste receptor T1R2+3. TAS1R2 is formed as a dimer of the TAS1R2 and TAS1R3 proteins. Moreover, the TAS1R2 protein is not functional without formation of the 2+3 heterodimer. Another interesting quality of the TAS1R2 and TAS1R1 genes is their spontaneous activity in the absence of the extracellular domains and binding ligands. This may mean that the extracellular domain regulates function of the receptor by preventing spontaneous action as well as binding to activating ligands such as sucrose. |
| Supplier | Abbkine |
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