| Product Name | DUSP22 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to DUSP22 |
| Synonyms | Dual specificity protein phosphatase 22 antibody; DUS22_HUMAN antibody; Dusp22 antibody; JNK stimulatory phosphatase 1 antibody; JNK-stimulatory phosphatase-1 antibody; JSP 1 antibody; JSP-1 antibody; JSP1 antibody; LMW DSP2 antibody; LMW-DSP2 antibody; Low molecular weight dual specificity phosphatase 2 antibody; MAP kinase phosphatase x antibody; Mitogen activated protein kinase phosphatase x antibody; Mitogen-activated protein kinase phosphatase x antibody; MKP-x antibody; MKPX antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human DUSP22 |
| Isotype | IgG |
| Target | DUSP22 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q9NRW4 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes. |
| Supplier | Cusabio |
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