Product Name | DUSP22 Antibody |
---|---|
Description | Rabbit polyclonal antibody to DUSP22 |
Synonyms | Dual specificity protein phosphatase 22 antibody; DUS22_HUMAN antibody; Dusp22 antibody; JNK stimulatory phosphatase 1 antibody; JNK-stimulatory phosphatase-1 antibody; JSP 1 antibody; JSP-1 antibody; JSP1 antibody; LMW DSP2 antibody; LMW-DSP2 antibody; Low molecular weight dual specificity phosphatase 2 antibody; MAP kinase phosphatase x antibody; Mitogen activated protein kinase phosphatase x antibody; Mitogen-activated protein kinase phosphatase x antibody; MKP-x antibody; MKPX antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Fusion protein of human DUSP22 |
Isotype | IgG |
Target | DUSP22 |
Reactivity | Human, Mouse |
Applications | ELISA, IHC |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | Q9NRW4 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP22 dephosphorylates ERK2 MAP kinase and JNK. DUSP22 displays highest in thymus, but it is also detectable in monocytes and lymphocytes. |
Supplier | Cusabio |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.