| Product Name | DUSP8 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to DUSP8 |
| Synonyms | C11orf81 antibody; Chromosome 11 open reading frame 81 antibody; Deubiquitinating enzyme 8 antibody; Dual Specificity Phosphatase 8 antibody; Dual specificity phosphatase M3/6 antibody; Dual specificity protein phosphatase 8 antibody; Dual specificity protein phosphatase hVH 5 antibody; Dual specificity protein phosphatase hVH-5 antibody; DUS8 antibody; DUS8_HUMAN antibody; DUSP8 antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; FLJ42476 antibody; FLJ42958 antibody; H1 phosphatase vaccinia virus homolog antibody; H1 phosphatase; vaccinia virus; homolog of antibody; HB5 antibody; hUBPy antibody; HVH5 antibody; HVH8 antibody; M3/6; mouse; homolog of antibody; Neuronal tyrosine threonine phosphatase 1 antibody; Serine/threonine specific protein phosphatase antibody; Ubiquitin carboxyl terminal hydrolase 8 antibody; Ubiquitin specific processing protease 8 antibody; Ubiquitin thiolesterase 8 antibody; VH5 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human DUSP8 |
| Isotype | IgG |
| Target | DUSP8 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q13202 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. |
| Supplier | Cusabio |
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