| Product Name | DYNLL1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to Dynein light chain 1,cytoplasmic |
| Synonyms | 8 kDa dynein light chain antibody; 8kDLC antibody; Cytoplasmic dynein light polypeptide antibody; DLC1 antibody; DLC8 antibody; DNCL1 antibody; DNCLC1 antibody; DYL1_HUMAN antibody; Dynein ; cytoplasmic; light chain 1 antibody; Dynein light chain 1 cytoplasmic antibody; Dynein light chain 1; cytoplasmic antibody; Dynein light chain LC8 type 1 antibody; Dynein light chain LC8-type 1 antibody; Dynein; cytoplasmic; light polypeptide 1 antibody; Dynein; light chain; LC8-type 1 antibody; DYNLL1 antibody; HDLC1 antibody; LC8 antibody; LC8a antibody; MGC126137 antibody; MGC126138 antibody; MGC72986 antibody; PIN antibody; Protein inhibitor of neuronal nitric oxide synthase antibody; Protein inhibitor of neuronal NOS antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human Dynein light chain 1, cytoplasmic protein (1-89AA) |
| Isotype | IgG |
| Target | DYNLL1 |
| Reactivity | Human |
| Applications | ELISA, IF, IHC, WB |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | P63167 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Binds and inhibits the catalytic activity of neuronal nitric oxide synthase. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity. |
| Supplier | Cusabio |
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