| Product Name | DYNLT3, 1-116aa, Human |
|---|---|
| Description | DYNLT3 is a member of a subclass of dynein light chains. This protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. It may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. DYNLT3 may also function independently of dynein as a transcriptional modulator. Recombinant human DYNLT3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Dynein light chain Tctex-type 3, RP3; TCTE1L; TCTEX1L |
| Host | E. coli |
| Molecular Weight | 23 kDa (211aa), confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMEEYHRH CDEVGFNAEE AHNIVKECVD GVLGGEDYNH NNINQWTASI VEQSLTHLVK LGKAYKYIVT CAVVQKSAYG FHTASSCFWD TTSDGTCTVR WENRTMNCIV NVFAIAIVL |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| Purity | > 80% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Yeh TY, et al. (2005). J Cell Sci. 1;118(Pt 15):3431-43. |
| Background | DYNLT3 is a member of a subclass of dynein light chains. This protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. It may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. DYNLT3 may also function independently of dynein as a transcriptional modulator. Recombinant human DYNLT3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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