| Product Name | EFNA2 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to EFNA2 |
| Synonyms | EFNA 2 antibody; efna2 antibody; EFNA2_HUMAN antibody; ELF1 antibody; Eph related receptor tyrosine kinase ligand 6 antibody; EPH-related receptor tyrosine kinase ligand 6 antibody; Ephrin-A2 antibody; EphrinA2 antibody; EPLG6 antibody; HEK7 L antibody; HEK7 ligand antibody; HEK7-L antibody; HEK7L antibody; LERK 6 antibody; LERK-6 antibody; LERK6 antibody; Ligand of eph related kinase 6 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from Internal of human EFNA2. |
| Isotype | IgG |
| Target | EFNA2 |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | O43921 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis By similarity. Cerretti D.P., Genomics 47:131-135(1998). Aasheim H.C., Biochem. Biophys. Res. Commun. 252:378-382(1998). Grimwood J., Nature 428:529-535(2004). |
| Supplier | Cusabio |
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