Egr-2 Polyclonal Antibody

Category: Antibodies
Catalog
E-AB-31292
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Product Name Egr-2 Polyclonal Antibody
Description The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.EGR2 (Early Growth Response 2) is a Protein Coding gene. Diseases associated with EGR2 include Neuropathy, Congenital Hypomyelinating and Charcot-Marie-Tooth Disease, Type 1D. Among its related pathways are Toll-like Receptor Signaling Pathway and HTLV-I infection. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and ligase activity. An important paralog of this gene is EGR3.
Synonyms EGR1, KROX24, ZNF225, Early growth response protein 1, EGR-1, AT225, Nerve growth factor-induced protein A, NGFI-A, Transcription factor ETR103, Transcription factor Zif268, Zinc finger protein 225, Zinc finger protein Krox-24, EGR2, KROX20
Host Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human Egr-2
Isotype IgG
Reactivity Human, Mouse, Rat
Applications ELISA, IF, IHC, WB
Form PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Uniprot P18146/P11161
Background The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.EGR2 (Early Growth Response 2) is a Protein Coding gene. Diseases associated with EGR2 include Neuropathy, Congenital Hypomyelinating and Charcot-Marie-Tooth Disease, Type 1D. Among its related pathways are Toll-like Receptor Signaling Pathway and HTLV-I infection. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and ligase activity. An important paralog of this gene is EGR3.
Supplier Elabscience

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