| Product Name | EGR2 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to EGR2 |
| Synonyms | AT591 antibody; CMT1D antibody; CMT4E antibody; DKFZp686J1957 antibody; E3 SUMO-protein ligase EGR2 antibody; Early growth response 2 antibody; Early growth response protein 2 antibody; EGR-2 antibody; egr2 antibody; EGR2_HUMAN antibody; FLJ14547 antibody; KROX 20 Drosophila homolog antibody; Krox 20 homolog Drosophila antibody; KROX-20; Drosophila; homolog (early growth response-2) antibody; KROX20 antibody; Krox20 protein antibody; Zinc finger protein Krox-20 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from C-terminal of human EGR2. |
| Isotype | IgG |
| Target | EGR2 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | P11161 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Joseph L.J., Proc. Natl. Acad. Sci. U.S.A. 85:7164-7168(1988). Warner L.E., Nat. Genet. 18:382-384(1998). Bechtel S., BMC Genomics 8:399-399(2007). |
| Supplier | Cusabio |
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