| Product Name | EID1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to EID1 |
| Synonyms | 21 kDa pRb associated protein antibody; 21 kDa pRb-associated protein antibody; C15orf3 antibody; CBP antibody; Chromosome 15 open reading frame 3 antibody; CREBBP/EP300 inhibitor 1 antibody; CREBBP/EP300 inhibitory protein 1 antibody; CRI 1 antibody; CRI1 antibody; E1A like inhibitor of differentiation antibody; E1A-like inhibitor of differentiation 1 antibody; EID 1 antibody; EID-1 antibody; EID1 antibody; EID1_HUMAN antibody; EP300 interacting inhibitor of differentiation 1 antibody; EP300-interacting inhibitor of differentiation 1 antibody; IRO45620 antibody; MGC138883 antibody; MGC138884 antibody; NB4 apoptosis related protein antibody; PNAS 22 antibody; PNAS22 antibody; PTD014 antibody; Rb and p300 binding protein EID 1 antibody; Rb and p300 binding protein EID1 antibody; RBP21 antibody; Retinoblastoma protein associated protein antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human EID1 |
| Isotype | IgG |
| Target | EID1 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q9Y6B2 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator. |
| Supplier | Cusabio |
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