| Product Name | EID3 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to EID3 |
| Synonyms | E1A-like inhibitor of differentiation 3 antibody; EID 3 antibody; EID-1-like inhibitor of differentiation 3 antibody; EID-3 antibody; EID3 antibody; EID3_HUMAN antibody; EP300 interacting inhibitor of differentiation 3 antibody; EP300-interacting inhibitor of differentiation 3 antibody; FLJ25832 antibody; Non-SMC element 4; S. cerevisiae; homolog of; B antibody; Non-structural maintenance of chromosomes element 4 homolog B antibody; NSE4B antibody; NSMCE4B antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human EID3 |
| Isotype | IgG |
| Target | EID3 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q8N140 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter. |
| Supplier | Cusabio |
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