| Product Name | EIF3J Antibody, HRP conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against EIF3J conjugated to HRP. |
| Synonyms | eIF 3 alpha antibody; eIF-3-alpha antibody; eIF3 alpha antibody; eIF3 p35 antibody; eIF3j antibody; EIF3J_HUMAN antibody; EIF3S 1 antibody; EIF3S1 antibody; Eukaryotic translation initiation factor 3 subunit 1 antibody; Eukaryotic translation initiation factor 3 subunit J antibody; Eukaryotic translation initiation factor 3; subunit 1 (alpha; 35kD) antibody; Eukaryotic translation initiation factor 3; subunit 1 alpha; 35kD antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | HRP |
| Immunogen | Recombinant Human Eukaryotic translation initiation factor 3 subunit J protein (5-115AA) |
| Isotype | IgG |
| Target | EIF3J |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Uniprot | O75822 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA. |
| Supplier | Cusabio |
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