| Product Name | ELAVL2, 1-346aa, Human |
|---|---|
| Description | ELAVL2 is a neural-specific RNA-binding protein that is known to bind to several 3' uTRs, including its own and also that of FOS and ID. This protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. Recombinant human ELAVL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | ELAV-like protein 2, ELAV-like protein 2, HEL-N1, HELN1, HuB |
| Host | E. coli |
| Molecular Weight | 44 kDa (401aa) confirmed by MALDI-TOF. |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMETQLSN GPTCNNTANG PTTINNNCSS PVDSGNTEDS KTNLIVNYLP QNMTQEELKS LFGSIGEIES CKLVRDKITG QSLGYGFVNY IDPKDAEKAI NTLNGLRLQT KTIKVSYARP SSASIRDANL YVSGLPKTMT QKELEQLFSQ YGRIITSRIL VDQVTGISRG VGFIRFDKRI EAEEAIKGLN GQKPPGATEP ITVKFANNPS QKTNQAILSQ LYQSPNRRYP GPLAQQAQRF RFSPMTIDGM TSLAGINIPG HPGTGWCIFV YNLAPDADES ILWQMFGPFG AVTNVKVIRD FNTNKCKGFG FVTMTNYDEA AMAIASLNGY RLGDRVLQVS FKTNKTHKA |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in PBS (pH 7.4) containing 30% glycerol, 1mM DTT. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 85 % by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles |
| References | Joeson L., et al. (2007) Mol. Cell. Proteomics 6:798-811. |
| Background | ELAVL2 is a neural-specific RNA-binding protein that is known to bind to several 3' uTRs, including its own and also that of FOS and ID. This protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. Recombinant human ELAVL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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