Elf-5 Polyclonal Antibody

Category: Antibodies
Catalog
E-AB-31305
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Product Name Elf-5 Polyclonal Antibody
Description The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms ELF5, ESE2, ETS-related transcription factor Elf-5, E74-like factor 5, Epithelium-restricted ESE-1-related Ets factor, Epithelium-specific Ets transcription factor 2, ESE-2
Host Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human Elf-5
Isotype IgG
Reactivity Human, Mouse
Applications ELISA, IF, WB
Form PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Uniprot Q9UKW6
Background The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Supplier Elabscience

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