| Product Name | EliKine™ Human β-hCG ELISA Kit |
|---|---|
| Description | EliKine™ Human β-hCG ELISA Kit has high sensitivity and excellent specificity for detection of Human β-hCG. No significant cross-reactivity or interference between Human β-hCG and analogues was observed. Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma. EliKine™ Human β-hCG ELISA Kit employs a two-site sandwich ELISA to quantitate β-hCG in samples. An antibody specific for β-hCG has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any β-hCG present is bound by the immobilized antibody. After removing any unbound substances, a HRP conjugated antibody specific for β-hCG is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of β-hCG bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | CGB, CGB3, choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-Beta, Choriogonadotropin Subunit Beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, Chorionic Gonadotropin beta Chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB |
| Detection Range | 8 IU/L-240 IU/L |
| Sensitivity | 2.0 IU/L |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids |
| Gene Id | 1082 |
| Storage | 2-8°C |
| Background | Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma. |
| Supplier | Abbkine |
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