| Product Name | EliKine™ Human LH ELISA Kit |
|---|---|
| Description | EliKine™ Human LH ELISA Kit has high sensitivity and excellent specificity for detection of Human LH. No significant cross-reactivity or interference between Human LH and analogues was observed. Luteinizing hormone (LH) is produced in both men and women from the anterior pituitary gland in response to luteinizing hormonereleasing hormone (LH-RH or Gn-RH), that is released by the hypothalamus. LH, also called interstitial cell-stimulating hormone (ICSH) in men, is glycoprotein with a molecular weight of approximately 30,000 Dalton. LH stimulates ovulation and ovarian steroid production in the female. In the male, LH controls Leydig cell secretion of testosterone. LH is elevated in Luteal phase of menstrual cycle, primary hypogonadism, Gonadotropin-secreting pituitary tumors and menopause. LH is deceased in hypothalamic Gn-RH deficiency, pituitary LH deficiency and ectopic steroid production. EliKine™ Human LH ELISA Kit employs a two-site sandwich ELISA to quantitate LH in samples. An antibody specific for LH has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any LH present is bound by the immobilized antibody. After removing any unbound substances, a HRP conjugated antibody specific for LH is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LH bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | LH-B, LHB, LSH-B, LSH-beta, LSHB_HUMAN, Luteinizing hormone subunit beta, Lutropin beta chain, Lutropin subunit beta |
| Detection Range | 2 IU/L-75 IU/L |
| Sensitivity | 0.5 IU/L |
| Reactivity | Human |
| Sample Types | Serum, Plasma, Other biological fluids |
| Gene Id | 3972 |
| Storage | 2-8°C |
| Background | Luteinizing hormone (LH) is produced in both men and women from the anterior pituitary gland in response to luteinizing hormonereleasing hormone (LH-RH or Gn-RH), that is released by the hypothalamus. LH, also called interstitial cell-stimulating hormone (ICSH) in men, is glycoprotein with a molecular weight of approximately 30,000 Dalton. LH stimulates ovulation and ovarian steroid production in the female. In the male, LH controls Leydig cell secretion of testosterone. LH is elevated in Luteal phase of menstrual cycle, primary hypogonadism, Gonadotropin-secreting pituitary tumors and menopause. LH is deceased in hypothalamic Gn-RH deficiency, pituitary LH deficiency and ectopic steroid production. |
| Supplier | Abbkine |
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