| Product Name | EndoPDI Antibody: ATTO 488 |
|---|---|
| Description | Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. EndoPDI mRNA and protein expression is induced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia (1). Mouse Anti-Human EndoPDI Monoclonal IgG2a |
| Synonyms | Thioredoxin domain containing 5; ERP46; UNQ364; MGC3178; FLJ21353; FLJ90810; thioredoxin related protein; endothelial protein disulphide isomeras Antibody |
| Host | Mouse |
| Clone | 2E7/7 |
| Immunogen | Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the EndoPDI protein |
| Isotype | IgG2a |
| Specificity | Detects ~48kDa. |
| Reactivity | Human |
| Applications | ELISA, ICC, IF, IHC, IP, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_001139021 . 81567 |
| Uniprot | Q8NBS9 |
| Background | Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. EndoPDI mRNA and protein expression is induced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia (1). |
| Supplier | Stressmarq Biosciences |
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