ENPP1 Antibody, HRP conjugated

Category: Antibodies
Catalog
CSB-PA007679LB01HU
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Product Name ENPP1 Antibody, HRP conjugated
Description Rabbit polyclonal antibody against ENPP1 conjugated to HRP
Synonyms Alkaline phosphodiesterase 1 antibody; ARHR2 antibody; COLED antibody; E-NPP 1 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 antibody; ENPP1 antibody; ENPP1_HUMAN antibody; Ly 41 antigen antibody; M6S1 antibody; Membrane component chromosome 6 surface marker 1 antibody; NPP1 antibody; NPPase antibody; NPPS antibody; Nucleotide pyrophosphatase antibody; PC 1 antibody; PC-1 antibody; PCA1 antibody; PDNP1 antibody; Phosphodiesterase I/nucleotide pyrophosphatase 1 antibody; Plasma cell membrane glycoprotein 1 antibody; Plasma-cell membrane glycoprotein PC-1 antibody
Host Rabbit
Clonality Polyclonal
Conjugate HRP
Immunogen Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 protein (1-75AA)
Isotype IgG
Target ENPP1
Reactivity Human
Applications ELISA
Form Liquid
Diluent Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Uniprot P22413
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.
Supplier Cusabio

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