ENPP2 Antibody

Category: Antibodies
Catalog
CSB-PA613427ESR1HU
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Product Name ENPP2 Antibody
Description Rabbit polyclonal antibody to ENPP2
Synonyms ATX antibody; ATX X antibody; Autotaxin antibody; Autotaxin t antibody; E NPP 2 antibody; E-NPP 2 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 antibody; Enpp2 antibody; ENPP2_HUMAN antibody; Extracellular lysophospholipase D antibody; FLJ26803 antibody; LysoPLD antibody; NPP2 antibody; PD IALPHA antibody; PDNP2 antibody; Phosphodiesterase I alpha antibody; Phosphodiesterase I/nucleotide pyrophosphatase 2 antibody; Plasma lysophospholipase D antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Recombinant human Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 protein (564-863AA)
Isotype IgG
Target ENPP2
Reactivity Human
Applications ELISA, IHC
Form Liquid
Diluent Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Uniprot Q13822
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Supplier Cusabio

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