| Product Name | EPHA1-specific Monoclonal Antibody |
|---|---|
| Description | EPHA1,also named as EPH,EPHT and EPHT1,belongs to ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events,particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Ligands in the ephrin-A subclass,including the prototype family member ephrin-A1 (B61),are membrane associated through glycosylphosphatidyl-inositol linkages,whereas ephrin-B subclass consists of ligands with transmembrane domains. The general role of the Eph family is in mediating repulsive cell-cell interaction. |
| Synonyms | EPH,EPH receptor A1,EPHA1,Ephrin type A receptor 1,EPHT,EPHT1 |
| Host | Mouse |
| Clone | 650 |
| Immunogen | Synthetic Peptide |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.1% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P21709 |
| Background | EPHA1,also named as EPH,EPHT and EPHT1,belongs to ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events,particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Ligands in the ephrin-A subclass,including the prototype family member ephrin-A1 (B61),are membrane associated through glycosylphosphatidyl-inositol linkages,whereas ephrin-B subclass consists of ligands with transmembrane domains. The general role of the Eph family is in mediating repulsive cell-cell interaction. |
| Supplier | Elabscience |
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