| Product Name | Epha4, 20-547aa, Mouse, Baculovirus |
|---|---|
| Description | Epha4, as known as ephrin type-A receptor 4, is a single-pass type 1 membrane protein which belongs to the protein kinase superfamily and ephrin receptor subfamily. This protein may play a role in a signal transduction process involved in hindbrain pattern formation. The ephrins and ephrin receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Recombinant mouse Epha4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques |
| Synonyms | Ephrin type-A receptor 4 , Epha4, 2900005c20Rik, AI385584, Cek8, Hek8, rb, Sek, Sek1, Tyro1 |
| Host | Virus |
| Molecular Weight | 21kDa (189aa), confirmed by MALDI-TOF |
| Amino Acid Sequence | VTGSRVYPAN EVTLLDSRSV QGELGWIASP LEGGWEEVSI MDEKNTPIRT YQVCNVMEAS QNNWLRTDWI TREGAQRVYI EIKFTLRDCN SLPGVMGTCK ETFNLYYYES DNDKERFIRE SQFGKIDTIA ADESFTQVDI GDRIMKLNTE IRDVGPLSKK GFYLAFQDVG ACIALVSVRV FYKKCPLTVR NLAQFPDTIT GADTSSLVEV RGSCVNNSEE KDVPKMYCGA DGEWLVPIGN CLCNAGHEEQ NGECQACKIG YYKALSTDAS CAKCPPHSYS VWEGATSCTC DRGFFRADND AASMPCTRPP SAPLNLISNV NETSVNLEWS SPQNTGGRQD ISYNVVCKKC GAGDPSKCRP CGSGVHYTPQ QNGLKTTRVS ITDLLAHTNY TFEIWAVNGV SKYNPSPDQS VSVTVTTNQA APSSIALVQA KEVTRYSVAL AWLEPDRPNG VILEYEVKYY EKDQNERSYR IVRTAARNTD IKGLNPLTSY VFHVRARTAA GYGDFSEPLE VTTNTVPSRI IGDGANSTLE HHHHHH |
| Tag | His-tag |
| Reactivity | Mouse |
| Applications | SDS-PAGE |
| Form | Liquid, in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Borgius L., et al. (2014) J. Neurosci. 34:3841-3853. Steinecke A., et al. (2014) Development 141:460-471. |
| Background | Epha4, as known as ephrin type-A receptor 4, is a single-pass type 1 membrane protein which belongs to the protein kinase superfamily and ephrin receptor subfamily. This protein may play a role in a signal transduction process involved in hindbrain pattern formation. The ephrins and ephrin receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Recombinant mouse Epha4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques |
| Supplier | ARP |
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