EYA4 Antibody, HRP conjugated

Category: Antibodies
Catalog
CSB-PA007909LB01HU
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Product Name EYA4 Antibody, HRP conjugated
Description Rabbit polyclonal antibody against EYA4 conjugated to HRP
Synonyms CMD1J antibody; Deafness, autosomal dominant 10 antibody; DFNA 10 antibody; DFNA10 antibody; dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody; dJ78N10.1 (eyes absent) antibody; EYA 4 antibody; eya4 antibody; EYA4_HUMAN antibody; Eyes absent 4 antibody; Eyes absent homolog 4 (Drosophila) antibody; Eyes absent homolog 4 antibody; HGNC:3522 antibody; OTTHUMP00000040267 antibody
Host Rabbit
Clonality Polyclonal
Conjugate HRP
Immunogen Recombinant Human Eyes absent homolog 4 protein (153-224AA)
Isotype IgG
Target EYA4
Reactivity Human
Applications ELISA
Form Liquid
Diluent Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Uniprot O95677
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity).
Supplier Cusabio

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