| Product Name | FABP5, 1-135aa, Human, Recombinant |
|---|---|
| Description | FABP5 is a member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to specifically bind fatty acids (FAs) with high affinity for stearic and linoleic acids. FABP5 is expressed in endothelial cells of the microvasculature of the placenta, heart, skeletal muscle, small intestine, lung, and renal medulla. FABP4 and FABP5 are closely related and both are expressed in adipocytes. Absence of FABP5 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Recombinant human FABP5 was expressed in E.coli and purified by conventional chromatography. |
| Synonyms | EFABP, E-FABP, PAFABP, PA-FABP, Fatty acid binding protein 5, Fatty acid-binding protein epidermal, FABP5, Fatty acid binding protein 5, fatty acid binding protein 5 (psoriasis-associated), |
| Host | E. coli |
| Molecular Weight | 16kDa (147aa), confirmed by MALDI-TOF. |
| Amino Acid Sequence | MATVQQLEGR WRLVDSKGFD EYMKELGVGI ALRKMGAMAK PDCIITCDGK NLTIKTESTL KTTQFSCTLG EKFEETTADG RKTQTVCNFT DGALVQHQEW DGKESTITRK LKDGKLVVEC VMNNVTCTRI YEKVE |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris pH 8.0 |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Hagens G., et al: (1999) Biochem.J ; 339 ( Pt 2): 419-27 Hohoff C., et al: (1999) Biochemistry ; 38 (38): 12229-39 |
| Background | FABP5 is a member of the intracellular fatty acid binding protein (FABP) family, which is known for the ability to specifically bind fatty acids (FAs) with high affinity for stearic and linoleic acids. FABP5 is expressed in endothelial cells of the microvasculature of the placenta, heart, skeletal muscle, small intestine, lung, and renal medulla. FABP4 and FABP5 are closely related and both are expressed in adipocytes. Absence of FABP5 resulted in increased systemic insulin sensitivity in two models of obesity and insulin resistance. Recombinant human FABP5 was expressed in E.coli and purified by conventional chromatography. |
| Supplier | ARP |
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