| Product Name | FAM20C Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to FAM20C |
| Synonyms | C76981 antibody; Dentin matrix protein 4 antibody; DKFZp547C074 antibody; DMP-4 antibody; DMP4 antibody; DMP4_HUMAN antibody; Extracellular serine/threonine protein kinase Fam20C antibody; Fam20c antibody; Family with sequence similarity 20 member C antibody; GEF CK antibody; Golgi enriched fraction casein kinase antibody; Protein FAM20C antibody; RNS antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Extracellular serine/threonine protein kinase FAM20C protein (107-224AA) |
| Isotype | IgG |
| Target | FAM20C |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Uniprot | Q8IXL6 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039). |
| Supplier | Cusabio |
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