| Product Name | FBN1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to FBN1 |
| Synonyms | 350 kDa glycoprotein component extracellular microfibril antibody; ACMICD antibody; FBN 1 antibody; FBN antibody; FBN1 antibody; FBN1_HUMAN antibody; Fibrillin 15 antibody; Fibrillin-1 antibody; Fibrillin1 antibody; Fibrillin15 antibody; GPHYSD2 antibody; Marfan syndrome antibody; MASS antibody; MFS 1 antibody; MFS1 antibody; OCTD antibody; SGS antibody; SSKS antibody; Weill Marchesani syndrome antibody; WMS antibody; WMS2 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from human Fibrillin-1. |
| Isotype | IgG |
| Target | FBN1 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | P35555 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. Ehab El-Hallous, J. Biol. Chem., Mar 2007; 282: 8935 - 8946. Shazia S. Chaudhry, J. Cell Biol., Jan 2007; 176: 355 - 367. Kerstin Tiedemann, J. Biol. Chem., Sep 2001; 276: 36035 - 36042. Liliana Schaefer, Am. J. Pathol., Aug 2004; 165: 383 - 396. |
| Supplier | Cusabio |
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