| Product Name | FBXL5 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to FBXL5 |
| Synonyms | F box and leucine rich repeat protein 5 antibody; F box protein FBL5 antibody; F box/LRR repeat protein 5 antibody; F-box and leucine-rich repeat protein 5 antibody; F-box protein FBL4/FBL5 antibody; F-box/LRR-repeat protein 5 antibody; FBL4 antibody; FBL5 antibody; FBXL5 antibody; FBXL5_HUMAN antibody; FLR1 antibody; p45SKP2 like protein antibody; p45SKP2-like protein antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human F-box/LRR-repeat protein 5 protein (1-310AA) |
| Isotype | IgG |
| Target | FBXL5 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot | Q9UKA1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued. |
| Supplier | Cusabio |
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