| Product Name | FCHO2 Antibody, FITC conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against FCHO2 conjugated to FITC. |
| Synonyms | FCHO2F-BAR domain only protein 2 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | FITC |
| Immunogen | Recombinant Human F-BAR domain only protein 2 protein (100-203AA) |
| Isotype | IgG |
| Target | FCHO2 |
| Reactivity | Human |
| Applications | ELISA, Dot Blot |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q0JRZ9 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor. |
| Supplier | Cusabio |
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