FEM1A Antibody

Category: Antibodies
Catalog
CSB-PA259482
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Product Name FEM1A Antibody
Description Rabbit polyclonal antibody to FEM1A
Synonyms AW611390 antibody; DKFZp762M136 antibody; EPRAP antibody; Fem-1 homolog a (C. elegans) antibody; Fem1 homolog a antibody; FEM1-alpha antibody; FEM1-alpha-A antibody; FEM1a antibody; FEM1a-A antibody; FEM1A_HUMAN antibody; Fem1aa antibody; Feminization 1 homolog a (C. elegans) antibody; Feminization 1 homolog a antibody; MGC114562 antibody; MGC117925 antibody; Prostaglandin E receptor 4-associated protein antibody; Protein fem-1 homolog A antibody; Protein fem-1 homolog A-A antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Synthetic peptide of human FEM1A
Isotype IgG
Target FEM1A
Reactivity Human
Applications ELISA, IHC
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot Q9BSK4
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family. FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes. FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit. It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4. FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children. FEM1A is considered a candidate gene for polycystic ovary syndrome.
Supplier Cusabio

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