FGF-23 Polyclonal Antibody

Category: Antibodies
Catalog
E-AB-33441
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Product Name FGF-23 Polyclonal Antibody
Description This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).
Synonyms FGF23; HYPF; Fibroblast growth factor 23; FGF-23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor
Host Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human FGF-23.
Isotype IgG
Reactivity Human
Applications ELISA, WB
Form PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Uniprot Q9GZV9
Background This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).
Supplier Elabscience

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