| Product Name | FGF12 Monoclonal Antibody |
|---|---|
| Description | FGF12 is a member of the fibroblast growth factor (FGF) family. FGF family members play important roles in embryogenesis,angiogenesis,and wound repair. FGF12 lacks the N-terminal signal sequence present in most of the FGF family members,but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells,this protein accumulated in the nucleus,but was not secreted. FGF12 plays an intracellular role in the inhibition of radiation-induced apoptosis. FGF12 is expressed abundantly in developing and adult nervous systems; therefore,FGF12 was thought to be related to nervous system development and function. |
| Synonyms | FGF 12,FGF12,FGF12B,FHF 1,FHF1,fibroblast growth factor 12,Myocyte activating factor |
| Host | Mouse |
| Clone | 610 |
| Immunogen | Fusion protein of FGF12 |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | PBS with 0.1% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P61328 |
| Background | FGF12 is a member of the fibroblast growth factor (FGF) family. FGF family members play important roles in embryogenesis,angiogenesis,and wound repair. FGF12 lacks the N-terminal signal sequence present in most of the FGF family members,but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells,this protein accumulated in the nucleus,but was not secreted. FGF12 plays an intracellular role in the inhibition of radiation-induced apoptosis. FGF12 is expressed abundantly in developing and adult nervous systems; therefore,FGF12 was thought to be related to nervous system development and function. |
| Supplier | Elabscience |
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