| Product Name | FGFR1 Monoclonal Antibody |
|---|---|
| Description | Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processed including embryonic development,cell proliferation,differentiation,migration,and tumorigenesis. Mutations in FGFR1 gene have been associated with Pfeiffer syndrome,Jackson-Weiss syndrome,Antley-Bixler syndrome,osteoglophonic dysplasia,squamous cell lung cancer and autosomal dominant Kallmann syndrome. Alternatively spliced variants which encode different protein isoforms have been described. |
| Synonyms | bFGF R 1,BFGFR,CD331,CEK,FGFBR,FGFR 1,FGFR1,FLG,FLJ99988,FLT 2,FLT2,Fms like tyrosine kinase 2,HBGFR,KAL2,N SAM,OGD,Proto oncogene c Fgr |
| Host | Mouse |
| Clone | 520 |
| Immunogen | Fusion protein of FGFR1 |
| Isotype | IgG2c |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P11362 |
| Background | Fibroblast growth factor receptor 1 (FGFR1) is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors. FGFR1 has been implicated in diverse biological processed including embryonic development,cell proliferation,differentiation,migration,and tumorigenesis. Mutations in FGFR1 gene have been associated with Pfeiffer syndrome,Jackson-Weiss syndrome,Antley-Bixler syndrome,osteoglophonic dysplasia,squamous cell lung cancer and autosomal dominant Kallmann syndrome. Alternatively spliced variants which encode different protein isoforms have been described. |
| Supplier | Elabscience |
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