| Product Name | FGG, 27-437aa, Human |
|---|---|
| Description | FGG, also Known as Fibrinogen gamma chain isoform gamma-A. FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, FGG is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Recombinant human FGG, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Fibrinogen gamma chain isoform gamma-A, Fibrinogen gamma chain |
| Host | E. coli |
| Molecular Weight | 69.9kDa (625aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSYVATRDN CCILDERFGS YCPTTCGIAD FLSTYQTKVD KDLQSLEDIL HQVENKTSEV KQLIKAIQLT YNPDESSKPN MIDAATLKSR KMLEEIMKYE ASILTHDSSI RYLQEIYNSN NQKIVNLKEK VAQLEAQCQE PCKDTVQIHD ITGKDCQDIA NKGAKQSGLY FIKPLKANQQ FLVYCEIDGS GNGWTVFQKR LDGSVDFKKN WIQYKEGFGH LSPTGTTEFW LGNEKIHLIS TQSAIPYALR VELEDWNGRT STADYAMFKV GPEADKYRLT YAYFAGGDAG DAFDGFDFGD DPSDKFFTSH NGMQFSTWDN DNDKFEGNCA EQDGSGWWMN KCHAGHLNGV YYQGGTYSKA STPNGYDNGI IWATWKTRWY SMKKTTMKII PFNRLTIGEG QQHHLGGAKQ AGDV |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate buffer saline (pH 7.4) containing 10% glycerol |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Abaeva AA.,et al. (2013) J. Biol. Chem. 288 (41), 29621-29632 |
| Background | FGG, also Known as Fibrinogen gamma chain isoform gamma-A. FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, FGG is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Recombinant human FGG, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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