Fibronectin Monoclonal Antibody

Category: Antibodies
Catalog
E-AB-27163
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Product Name Fibronectin Monoclonal Antibody
Description Fibronectin 1 (FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellular matrix (cellular FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms),made by fibroblasts,epithelial and other cell types,is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen,fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis,wound healing,hemostasis,host defense,and metastasis.
Synonyms CIG,Cold insoluble globulin,DKFZp686F10164,DKFZp686H0342,DKFZp686I1370,DKFZp686O13149,ED B,Fibronectin,fibronectin 1,FINC,FN,FN1,FNZ,GFND,GFND2,LETS,MSF
Host Mouse
Clone 46
Immunogen Fusion protein of Fibronectin
Isotype IgG1
Reactivity Human, Mouse
Applications ELISA, IF, WB
Form PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Uniprot P02751
Background Fibronectin 1 (FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellular matrix (cellular FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms),made by fibroblasts,epithelial and other cell types,is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen,fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis,wound healing,hemostasis,host defense,and metastasis.
Supplier Elabscience

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